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by Anthony Roberts - Testosterone is a hormone
produced predominantly in the testes of males. It
is responsible for nearly all of the sexual traits
in males. This specific version is Testosterone
with the Phenylpropionate ester attached. It has
an active life of 4-5 day. Release time-wise, it
is directly in the middle of the
Propionate
(short) and
Cypionate (long) versions of Testosterone. It
is recommended to inject this version two times
per week, although many prefer every third day.
Background
Testosterone was first synthesized by being isolated
from bulls’ testicles in 1935. Many pharmaceutical
forms and derivatives have been created since.
This version of Testosterone was originally manufactured
by the Sicomed Pharmaceutical house under the brand
name, “Testolent.” For many years, Testosterone
Phenylpropionate was difficult to obtain but has
recently been made more available by underground
labs.
Steroid Action
Testosterone is responsible for promoting health
and well-being through enhanced libido, energy,
immunity, increased fat loss, gaining and maintaining
lean muscle mass, preventing Osteoporosis (loss
of bone density) and possible protection against
heart disease. Testosterone is also responsible
for normal growth and development of male sex organs
and maintenance of secondary sex characteristics.
Secondary sex characteristics are specific traits
that separate the two sexes, but are not directly
part of the reproductive system, for example: chest
and facial hair, a distinguished jaw line, broad
shoulders and increased muscle mass. Testosterone
binds to the Androgen Receptors (AR), which thus
causes accelerated muscle gain, fat loss, and muscle
repair and growth. These mechanisms are stimulated
by activation of the Androgen Receptors (either
directly or as DHT).
There are many possible side-effects associated
with its use. This product also has a high level
of aromatization into estrogen and coverts to
DHT (dihydrotestosterone)
as well. Conversion to estrogen, the female sex
hormone, creates a high risk of gynecomastia (formation
of breast tissue in males) and water retention.
Supplementing Testosterone into your body will
result in the shutting down of the body's natural
production of the hormone. The severity of side
effects depend mostly on the dose and duration of
circulating free testosterone and its conversion
to substrates. Testosterone's anabolic/androgenic
effects are dependant upon dosage, therefore, the
higher the dose the higher the muscle building effect.
Testosterone also promotes aggressive and dominant
behavior.
Testosterone is possibly the best mass builder
known to man and recommended as the base of any
mass building cycle.
Technical Data
Testosterone's anabolic/androgenic effects are
dependant upon the dose administered; usually the
higher the dose, the better the results (1). In
a study done on Testosterone (Enanthate), a dose
as high as 600 mg's (per week) produced better results
in subjects compared to those who received lower
doses. At the highest dose, 600 mg/week, the greatest
results were achieved in comparison to any of the
lower doses studied. The highest fat loss, most
muscle growth, and increased size and strength were
achieved at the higher dose (2). In the same study,
HDL cholesterol was lowered and the subjects experienced
acne. There was roughly a 15% gain in Lean Body
Mass from 20 weeks of 600 mg/week of Testosterone
therapy.
Overall, the most common report by subjects using
testosterone was immense gains in strength (3) as
well as alterations in size, shape, and appearance
of the muscle (4).
Due to stimulation of the Androgen Receptors
(either directly or as DHT), accelerated muscle
gain, fat loss, increased muscle repair and growth
was experienced (5),(6). Testosterone binds to the
A.R. on fat cells; therefore, adipose (fat) tissue
can be broken down more readily while new fat formation
is prevented (7). Since the body is building muscle
at an accelerated rate, more ingested food is shuttled
directly to the muscle tissue (this is known as
nutrient portioning) and away from fat. This is
another indirect effect of testosterone on fat loss.
Testosterone also promotes glycogen synthesis, which
is activated by insulin in response to high glucose
levels (8). Glycogen provides fuel to the muscle;
therefore endurance and strength increases were
reported during severe muscle breakdown in intense
training and workouts.
User Notes
I recently had the opportunity to try Testosterone
Phenylpropionate in one of my cycles. I think that
the primary advantage of this stuff is that underground
manufacturers are not scared to dose it at 200 mg/ml,
unlike other short(ish) esters like propionate…where
100 mg/ml is the typical dose.
I was using it at 200 mg every other day, and
found that was enough to raise my testosterone levels
to roughly 1.5x the high end of normal.
My gains on this type of testosterone were typical
of any kind of testosterone I have ever used (regardless
of ester) although the water retention was similar
to propionate (low).
Although it wasn’t necessary, I chose to inject
every other day although the active life of this
compound would have allowed me to inject once every
third or even fourth day. It’s a natural match in
a cycle with Nandrolone Phenylpropionate, as both
can be injected on the same day with the same frequency.
Since water retention is low with this compound,
it is probably the most versatile form of esterified
testosterone available on the market…it builds mass
like the long esters, doesn’t require very frequent
injections, and doesn’t cause water retention like
cypionate or enanthate.
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| Substance Name |
Testosterone phenylpropionate,
Testosterone 17-phenylpropionate |
| Chemical Name |
Androst-4-en-3-one, 17-(1-oxo-3-phenylpropoxy)-,
(17-beta)- (9CI) |
| Systematic Name |
IUPAC: [(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]
3-phenylpropanoate |
| CAS Number |
1255-49-8; 58-22-0 (base) |
| Merck Index Number |
Merck 11, 9109 |
| Chemical Formula |
C28-H36-O3 |
| Molecular Weight |
420.589 g/mol |
| Bioavailability |
99% |
| Metabolism |
Liver, Testis and Prostate |
| Elimination Half Life |
1-12 days |
| Excretion |
Urinary |
| Legal Status |
Prescription
only (US); DEA Schedule III (US) |
| Route of Administration |
Intramuscular |
References
- J Lab Clin Med. 1995 Mar;125(3):326-33.
- Am J Physiol Endocrinol Metab. 2001 Dec;281(6):E1172-81.
- J Lab Clin Med. 1995 Mar;125(3):326-33.
- Am J Physiol. 1998 Nov;275(5 Pt 1):E864-712
- J Clin Endocrinol Metab. 1997 Feb;82(2):407-13
- Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E601-7.
- Curr Opin Clin Nutr Metab Care. 2004 May;7(3):271-7.
- Curr Pharm Biotechnol. 2004 Oct;5(5):459-70.
- J Clin Endocrinol Metab. 2004 Oct;89(10):5245-55.
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