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by Bill Roberts - Propecia (finasteride)
is used to treat male pattern baldness (androgenic
alopecia) in men. [It is also used in combination
with doxazosin in the treatment of benign prostatic
hyperplasia (BPH).] Finasteride is an orally active
testosterone Type II 5-alpha reductase inhibitor,
inhibiting the enzyme that converts testosterone
to dihydrotestosterone (DHT). Topically (on the
scalp itself) it is of some effect in minimizing
further hair loss. In combination with Nizoral and
spironolactone (which smells awful, by the way)
it can actually reverse loss moderately.
Oral use though will reduce
DHT levels
systemically, which may adversely affect training
and sex drive.
For use in cycles with
testosterone, I don’t
think it is bad at all. One simply doesn’t want
less DHT than normal. As the amount of testosterone
in the system increases, the amount of finasteride
needed to keep levels down to normal increases.
I consider 5 mg/day reasonable at the gram per week
level, and proportionally less at lower dosages
of testosterone.
I personally wouldn't use more than the recommended
pharmaceutical dosage, or 5 mg/day. More might not
be safe and might at some point cause
DHT levels
to become abnormally low.
Finasteride is the chemical
name of active ingredient in Proscar and Propecia.
Proscar and Propecia are registered
trademarks of Merck & Co. Inc. in the United States
and/or other countries.
Finasteride
Resources
Finasteride Pictures
Propecia Prescribing Information
Proscar Prescribing Information
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Substance name
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Finasteride [USAN:INN] |
| Chemical name* |
17beta-(N-tert-butylcarbamoyl)-4-aza-5
alpha-androst-1-en-3-one |
| Systematic name |
|
| Index name |
4-Azaandrost-1-ene-17-carboxamide, N-(1,1-dimethylethyl)-3-oxo-,
(5alpha,17beta)- |
| CAS number |
98319-26-7 |
| Merck Index Number |
|
| Molecular formula |
C23-H36-N2-O2 |
| Molecular weight |
372.549 |
| Pregnancy category |
X |
| Legal status |
Prescription
only (US) |
| Routes of administration |
Oral, Topical |
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